Industrial Lyophilizer Freeze Drying Equipment

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Project Description

Industrial Lyophilizer Freeze Drying Equipment

  • Professional Pharmaceutical Lyophilizer, Economical Food Freeze Dryer.

  • Overseas installation & test service.

  • Factory visit contact info@toption-china.com 24h/7days service.

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Industrial Lyophilizer Freeze Drying Equipment

GZLY suitable for medical and pharmaceutical vacuum freeze dryer

  • GZLY series freeze dryers use double color touch screen and PLC as control center ,control system stable and reliable. it can store 33groups of freeze drying program , and each program can be set up 36 segments.
  • It can display freeze drying curve and automatically records data. Freeze drying data can be output by USB flask disk. This model is suitable for pilot scale and small scale production.
  • GZLY series freeze dryers use Bitzer refrigeration unit,condenser temperature can reach<-75℃ , performance stable . It meets national relative standards ,according to GMP and implementation guidelines of GMP, and GB/T522 6.1-1996.
Lyophilizer

GZLY-1

GZLY-2

GZLY-3

GZLY-5

GZLY-10

GZLY-15

GZLY-20

GZLY-30

GZLY-40

Freeze drying area

1.152

2.16

3.24

5.25

10.5

15

20.2

30

40

Condenser temperature

< -75℃ (no-load)

Partition board temperature

≤ -55℃ (no-load)

control accuracy

±1℃

Vacuum degree

<  5Pa (no-load)

Cooling method

water cooling

Water capture capacity

20Kg/24h

40Kg/24h

60Kg/24h

100kg/24h

200kg/24h

300kg/24h

400kg/24h

600kg/24h

800kg/24h

Partition board size

600 x 480 x 20mm*4+1

600 x 900 x 20mm*4+1

600 x 900 x 20mm*6+1

750 x 1000 x 20mm*7+1

1520 x 990mm*7+1

1520 x 990mm*10+1

1520 x 1210mm*11+1

1500 x 1800mm*11+1

1500 x 1800mm*15+1

Installed Powe

15kw

15kw

18kw

20kw

50kw

83kw

105

145

170

Weight

1500kg

2600kg

2800kg

4200kg

7000kg

9000kg

11000kg

15000kg

20000kg

Dimension(mm)

2500x1100x2000

3500x1300x2000

2800x1200x2500

4000x1500x2500

6700×2100×3600

6500x2300x3400

7400x2300x3800

9200x2400x4000

9400x2400x4500

Bulk capacity Thickness:10mm

10L

20L

30L

50L

200L

300L

450L

600L

850L

Vial loading
number (pcs)

Ф12mm8400

Ф12mm12600

Ф12mm16000

Ф12mm35000

Ф12mm65300

Ф12mm95700

Ф12mm130400

Ф12mm187700

Ф12mm56000

Ф16mm4706

Ф16mm6800

Ф16mm10000

Ф16mm24800

Ф16mm46400

Ф16mm66400

Ф16mm92800

Ф16mm133600

Ф16mm82200

Ф22mm2428

Ф22mm3600

Ф22mm5300

Ф22mm12700

Ф22mm23700

Ф22mm33900

Ф22mm47400

Ф22mm68300

Ф22mm93000

GZL series vacuum freeze dryer

  • Pre-Freezing and drying process are both finished on shelf.
  • Silicon oil as circulation medium, with high accuracy of temperature control. Shelf temperature uniformity ≤ 1℃ , with uniform drying effect.
  • Shelf temperature adjustable, controlled, suitable for pilot and production.
  • Drying chamber and condenser as separated structure, with better water capture capacity and shorter drying time.
  • Touch screen operation,PLC control, display drying curve.
  • Square tray easy to operate and clean.
  • With charging valve, to fill dry inert gas.
  • Optional eutectic point test functions.
  • Optional PC software to realize the remote control.
  • Ozone disinfection function is optional.
Lyophilizer

GZL-1

GZL-2

GZL-3

GZL-5

GZL-10

GZL-15

GZL-20

GZL-30

GZL-40

Freeze drying area

1.152

2.16

3.24

5.25

10.5

15

20.2

30

40

Condenser temperature

< -75℃ (no-load)

Partition board temperature

≤ -55℃ (no-load)

Control accuracy

±1℃

Vacuum degree

<  5Pa (no-load)

Cooling method

water cooling

Water capture capacity

15Kg/24h

30Kg/24h

45Kg/24h

100kg/24h

200kg/24h

300kg/24h

400kg/24h

600kg/24h

800kg/24h

Partition board size

600 x 480 x 20mm*4+1

600 x 900 x 20mm*4+1

600 x 900 x 20mm*6+1

750 x 1000 x 20mm*7+1

1520 x 990mm*7+1

1520 x 990mm*10+1

1520 x 1210mm*11+1

1500 x 1800mm*11+1

1500 x 1800mm*15+1

Installed Powe

12kw

14kw

16kw

20kw

50kw

75kw

100

145

170

Weight

1200kg

2000kg

2800kg

3500kg

6500kg

8000kg

95000kg

15000kg

20000kg

Dimension(mm)

2500x1100x2000

3500x1300x2000

2800x1200x2500

4000x1500x2500

6700×2100×3600

6500x2300x3400

7400x2300x3800

9200x2400x4000

9400x2400x4500

Bulk capacity
Thickness:10mm

10L

20L

30L

50L

200L

300L

450L

600L

850L

Vial loading
number (pcs)

Ф12mm8400

Ф12mm12600

Ф12mm16000

Ф12mm35000

Ф12mm65300

Ф12mm95700

Ф12mm130400

Ф12mm187700

Ф12mm256000

Ф16mm4706

Ф16mm6800

Ф16mm10000

Ф16mm24800

Ф16mm46400

Ф16mm66400

Ф16mm92800

Ф16mm133600

Ф16mm182200

Ф22mm2428

Ф22mm3600

Ф22mm5300

Ф22mm12700

Ф22mm23700

Ф22mm33900

Ф22mm47400

Ф22mm68300

Ф22mm93000

Customizable CIP & SIP System Of Vacuum Freeze Drying Equipment

CIP and SIP system freeze dryer  is designed based on mature technology, use top quality material and parts which is widely accepted in pharmaceutical industry. Its manufacturing process use the most advanced technology, equipment totally meet CGMP standard, software meets 21 CFR Part 11 standard.

  • Freeze drying chamber / door / shelf

Freeze drying chamber is a kind of pressure vessel and products finish its vacuum freeze drying process in it. Chamber body generally use stainless steel square box, this reasonable structure design could make clean be more convenient and reduce the blind angle.

Put products in shelf, through freezing medium control temperature up/down,to achieve prefreezing and sublimation dehydration, besides, the stoppering can be fulfilled by shelves before products  exiting from the chamber. Use indirect cooling and heating method. Every shelf through special design, produce and processing, so could achieve uniform cooling and heating.

  • Refrigerating system / Vacuum system / Circulating system

Cooling system is consist of refrigerating compressor, water cooled condenser, throttle valve, evaporator,etc, provide cooling source for freeze drying chamber and vacuum condenser.

Circulating system through freezing medium to control shelf temperature, circulating pump drive freezing medium circulating.

  • Isolation Valve

The isolation valve allows proceeding with the product loading, unloading and freezing while the condenser is defrosted. In addition, the isolation valve can be used to test the degree of product drying by measuring the pressure rising during a preset closing time.

  • Hydraulic System/ CIP/ SIP

This system is used for feeding and discharging materials through lifting and dropping the shelves. At the same time, it is good for cleaning the chamber. Besides, the stopper can be pressed into penicillin bottle. It is also used for freezing and drying scattering material.

CIP could run automatically or manually through control program, whole sterilization process finish automatically.

Whole parts meet FDA/ CGMP standard.

Food Industrial Lyophilizer

GZVF series freeze dryers use double color touch screen and PLC as control center ,control system stable and reliable. it can store 33groups of freeze drying program , and each program can be set up 36 segments. It can display freeze drying curve and automatically records data.Freeze drying data can be output by USB flask disk.

GZVF series freeze dryers use Bitzer refrigeration unit,condenser temperature can reach  < -75℃ , performance stable .This model is suitable for production.

Food lyophilizer

GZVF-2

GZVF-5

GZVF-12

GZVF-16

GZVF-33

GZVF-44

Drying chamber

Shelf aream 2

2.4

5.9

12

16

33

44

Drying chamber sizem

Φ0.75 * 0.9

Φ1.1 * 1.2

Φ1.4 * 1.5

Φ1.5 * 2.1

Φ1600 * 3600

Φ1800 * 3600

Shelf layers

6+1

8+1

12+1

12+1

14+1

14+1

Shelf sizemm

500 * 800

1050 * 700

1200 * 800

1800 * 800

3100 * 800

3600 * 1000

Shelf spacingmm

70

70

70

75

75

758

Trolley number(set)

N/A

1

2

Trolley number(set)

N/A

1

2

Tray sizemm

350X500

350X500

400X600

400X600

400X500

400X500

Trays number (pcs)

24

64

96

144

336

448

Heating way

heat conductive oil circulation

Temperature range

room temperature~120

control accuracy

±1℃

condenser

Max. Ice capacity Kg

24

75

150

225

450

600

Ice capacity(kg/day)

20

60

100

150

300

400

Lowest temperature

-85

Temperature lowing style

direct evaporation

Defrosting method

warm water spray

basic parameters

final vacuumPa

5

Installed powerKw

6

12

25

37

72

104

cooling waterm3/h

air cooling

8 or air cooling

15 or air cooling

22 or air cooling

50

60

cooling water pipe dia

N/A

1 1/4″or N/A

1 1/2″ or  N/A

1 1/2″ or  N/A

2″

2″

dimensionm

1.5×1.5

3×2

4×2.2

5×2.3

8×2.6

9×3.2

heightm

2

2.2

2.3

2.3

2.6

3.2

weight

1.3

2.5

4

6

15

20

Main features of food & fruit industrial freeze drying equipment:

1.Vertical cylindrical condenser,compact structure,with good water capture capacity, no dead corner, easy for defrosting and cleaning.

2. Refrigeration system protection control device: adopt international famous brand products, accurate, stable, safe and reliable.

3. High pressure protection system: when the system exhaust pressure more than allowed, refrigeration unit running will be automatically cut off , to prevent accidents.

4. Middle pressure regulation system: in the double-stage refrigeration system, proper middle pressure are very important for operation performance and life of the refrigeration system. When middle pressure below the set value, the system will automatically start to adjust. Create conditions for the realization of the lyophilizer unmanned operation.

5. Oil pressure protection system: when the long time operation of the refrigerator, monitor the hydraulic pressure of the refrigerator, prevent refrigerator damage because of oil lack.

6. The motor temperature protection system: when the refrigerator motor temperature higher than the set value, in order to protect the refrigerator, the system will automatically stop the operation of the refrigerator.

7. Oil return at low temperature regulating system: when refrigerator works under very low evaporation temperature for long time , how to make the refrigeration oil well back to the crankcase is very important (lack of refrigeration oil in the system often causes refrigerator “burned”). When the crankcase lack of refrigeration oil, the system automatically start to establish proper oil level in the crankcase. Create conditions for the realization of the lyophilizer unmanned operation.

8. Exhaust temperature control system: when refrigerator exhaust temperature is too high, the system automatically start cooling system, to prevent the high pressure part of overtemperature operation. Create conditions for the realization of the lyophilizer unmanned operation.

9. Wet stroke prevention control system: when the high load operation of the refrigerator, the system can automatically go in the process of adjustment, prevent the wet stroke even “liquid impact phenomenon”. Create conditions for the realization of the lyophilizer unmanned operation.

10. Automatic liquid collection device: when the refrigerator is in standby mode, the device will automatically run , to collect stranded refrigerant in the system to storage tank, in order to start the freeze dryer again.

11. The machine start protection: when equipment has all security conditions , the machine will be able to start running.

12. whole machine structure longitudinal, front and back split type (convenient for transport and placing ).

13. Ozone disinfection function is optional.

Customer case of freeze drying equipment